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HSC Biology

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Module 2 | Blueprint of life

Focus 4: The structure of DNA can be changed and such changes may be reflected in the phenotype of the affected organism

Lesson 1 | DNA and polypeptide synthesis

  • Describe the process of DNA replication and explain its significance

  • Outline using a simple model, the process by which DNA controls the production of polypeptides

  • Perform a first-hand investigation or process information from secondary sources to develop a simple model for polypeptide synthesis

Lesson 2 | Beadle and Tatum

  • Explain the relationship between proteins and polypeptides

  • Analyse information from secondary sources to outline the evidence that led to Beadle and Tatum’s ‘one gene – one protein’ hypothesis and to explain why this was altered to the ‘one gene – one polypeptide’ hypothesis

Lesson 3 | Mutations

  • Explain how mutations in DNA may lead to the generation of new alleles

  • Discuss evidence for the mutagenic nature of radiation

  • Process information to construct a flowchart that shows that changes in DNA sequences can result in changes in cell activity

Lesson 4 | DNA and evolution

  • Explain how an understanding of the source of variation in organisms has provided support for Darwin’s Theory of evolution by natural selection

  • Process and analyse information from secondary sources to explain a modern example of ‘natural’ selection

  • Describe the concept of punctuated equilibrium in evolution and how it differs from the gradual process proposed by Darwin

  • Process information from secondary sources to describe and analyse the relative importance
    of the work of:
    – James Watson
    – Francis Crick
    – Rosalind Franklin
    – Maurice Wilkins

    in determining the structure of DNA and the impact of the quality of collaboration and communication on their scientific research

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    Lessons by expert teachers that cover the NSW HSC Biology Syllabus comprehensively.

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